Scientists separated THC, CBD, and other cannabinoids from cannabis in one commonly cited studies published in the 2007 Journal of Dermatological Science. They found that all the cannabinoids they tested were inhibiting the overproduction of keratinocytes (skin cells) typically seen in psoriasis when applied to human skin cells. But it's a little more complex than that: the researchers here also studied lab-made compounds that selectively inhibit CB1 or CB2 receptor activation, which are the receptors we normally think of when it comes to cannabinoids, and found that they didn't have a huge effect. It means that if any cannabinoids— including CBD — have a valuable role to play in treating psoriasis, such receptors will not mediate it. Essentially, we're only starting to understand what might happen here.
There are a few studies in rats that suggest transdermal CBD—meaning that the drug goes through the skin and into the bloodstream—may be useful in reducing arthritis-related pain and inflammation. But unless you’re a rat, that’s not going to mean much. And it certainly doesn’t tell us much about skin care. The “most robust” evidence we have for topical CBD is in the realm of pain control, Jeremy Davis, M.D., dermatologist at Ronald Reagan UCLA Medical Center, tells SELF. “But it’s being tried for just about everything else,” he says. And, as SELF explained previously, the evidence for CBD and pain relief isn’t all that convincing to begin with. That said, there are some theories about how CBD could lead to an anti-inflammatory effect on the skin, Jordan Tishler, M.D., medical cannabis specialist at Inhale in Boston, tells SELF, which could potentially be beneficial in treating conditions such as eczema, psoriasis, and rosacea.
For example, there is some evidence that CBD also has an effect on TRPV-1 and GPR55 receptors as well as its effects on CB1 and CB2 receptors, he says. Both are found in the skin and play a role in the signaling of inflammation an.
Is There Literally Any Reason for CBD to Be in Your Skin-Care Products?
These days you can do just about anything with CBD — including slathering it on your face: Cannabidiol (CBD) seems to take over the world of skin care. The compound, found in marijuana (cannabis) and hemp (also a form of cannabis, for the record), is supposed to have anti-inflammatory properties that might be beneficial to the skin, so it's no wonder it seems to be pretty much everywhere.
CBD beauty and skin-care products are available in Ulta, Sephora, and seemingly every corner of the internet. Brands like Herbivore, Kiehl’s, Peter Thomas Roth, Milk, Josie Maran, Saint Jane, and now even NYX all have CBD products.
Wait, remind me what CBD is again?
CBD is one of many cannabinoids found in cannabis, as previously explained by SELF. Tetrahydrocannabinol (THC) is the other major cannabinoid you may have heard of.
All CBD and THC bind to your body's cannabinoid receptors, which then cause a sequence of brain and spinal cord reactions that eventually produce their effects. Such effects may include euphoria, pain relief, and increased appetite when THC is involved.
When THC isn’t involved—when we’re just talking about CBD—much less is known about the potential effects.
What does the research tell us?
CBD's main alleged benefits in skin care tend to be associated with an anti-inflammatory reaction. But like many of the CBD trials for anxiety or pain management, the research is largely limited to laboratory and animal studies, says SELF Mary L. Stevenson, M.D., assistant professor of dermatology at the NYU Langone Medical Center.d pain. Nevertheless, Dr. Tishler notes, it remains to be seen whether or not CBD can actually cause significant changes in inflammation there (especially in the relatively small amounts found in an over-the-counter skin care serum).
When it comes to purchasing quality CBD Beauty Creams and Oils, you always want to make sure the products you are receiving come from a reputable source like Mary Jane’s CBD Dispensary. The main reason for picking products like this is to ensure quality and not receive any ineffective and/or potentially harmful products. With locations across several states to serve you, and our convenient online store, when you shop with Mary Jane’s you know you will only get the best CBD products on the market today.