More and more women say that items containing CBD and THC are the best resources they have to manage painful periods. Yet when compared to NSAIDs like Ibuprofen how do they measure up?
It turns out very well, but it's worth a closer look at why they work — exactly how the anti-inflammatory, pain relieving, muscle relaxing effects of cannabinoids interact with your time.
It addresses the real causes of pain & discomfort during your time, and how additional
In people who have periods, the uterus diligently prepares itself all month.
Next, the growing estrogen in your body has instructed your uterus to build up its endometrial tissue. Then, after you ovulated, and the progesterone boost helped plump up the tissue with arteries and blood — preparing to give an incoming embryo a warm welcome ... or, in this case, preparing for menstruation.
Once your body discovers it won’t be hosting a guest, your progesterone levels decreases — telling your uterus to roll up the welcome mat.
The body is taking back from the endometrium what it can, reducing the tissue and cutting off blood supply to its spiral-shaped arteries. Any proper blood flow, the endometrial tissue is getting ready to shed, so you will start feeling pain pangs.
The endometrium loses its defense without progesterone-producing a domino effect and the ideal conditions for inflammation.
While your progesterone decreased, inflammatory chemicals called prostaglandins increased. Prostaglandins (especially PGF2) peak during menstruation, resulting in the following effects:
(Note: some people claim that having sex helps to jump-start their periods — scientists believe that the prostaglandins in semen could contribute to this effect.)
We’re not trying to say that prostaglandins are all bad. They're essential for a healthy, functioning menstrual cycle.
Numerous studies , however , indicate that women with higher rates of prostaglandins may have more painful or heavy cycles — and therapies that can be particularly beneficial with lower levels of prostaglandin.
Scientists have recently discovered that — similar to NSAIDs — CBD also inhibits the enzyme which produces prostaglandin. However — unlike NSAIDs — CBD inhibits COX-2 preferentially over COX-1, suggesting its anti-inflammatory advantages come without the side effects of the gastrointestinal system.
Added bonus: Not only does CBD suppress the enzyme COX-2, but also CBD and THC physically stop the DNA from generating too much of this enzyme in the first place (through the receptor of PPARy).
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