Some users say Delta 8 will get you stoned. Some users mention feeling little or nothing in terms of intoxication. Delta 8 is psychoactive, but its intoxicating properties are not the same as delta 9 THC.
Similar to CBD, delta 8 also binds to CB-1 cannabinoid receptors in the nervous system, but delta-8 THC appears to react differently due to its slightly modified molecular structure. Users reported clear-headed, anxiolytic (anti-anxiety) and non-sedative effects. In certain ways, the results of delta 8 are the opposite of delta-9 THC. But they are all different, and the goods and strengths vary, so always err on the side of caution.
Delta-8 THC is usually generated in a distillate form. This is because it exists in such low concentrations in cannabis plants. Delta-8 can be distilled in a dense, transparent liquid that looks like any CBD distillate. This involves a multi-step process in which the plant passes through refining stages, including extraction, hibernation and decarboxylation.
Delta-8 distillate is sold in cartridges or syringes and can be vaporized with a regular cannabis pen or dab rig. It can also be combined with the flower to activate the Δ8THC potency stage. Since distillate is technically edible, it can be ingested orally, but little research has been done on the effects of delta-8 when it is metabolized in the body. A few delta-8-THC infused oral tinctures (for sublingual use) are also available.
The side effects of delta-8-THC as observed by the researchers were very negligible. Particularly when compared to some of the most popular pharmaceutical alternatives. Much further research is still needed, but delta-8-THC appears to possess many of the beneficial properties of cannabis, with slightly less adverse effects compared to delta-9-THC.
It's still a form of THC, however. Any cannabis product with high THC levels known as a psychoactive compound, should always be used with caution. Although delta-8-THC is said to be less psychoactive, online users have stated that it is possible to overdo it. Start slow and low and test your tolerance. Just because you're getting less high doesn't mean you're not getting high at all. One last thing to remember is that delta-8-THC can also cause redness in the eyes, particularly at higher doses.
Isn't it interesting how two cannabinoids, almost similar on a molecular level, can cause such different effects when interacting with the human endocannabinoid system?
Research on the benefits of Delta 8 has so far been minimal. Here are some of the possible benefits of current research:
A 1995 Life Sciences research shows the ability of delta-8 THC to alleviate symptoms of nausea with minimal side effects in infants, 'Delta-8-tetrahydrocannabinol was administered (18 mg/m2 in edible oil, p.o.) to eight children aged 3-13 years with various hematological cancers, treated with different antineoplastic drugs for up to 8 months. Vomiting was completely avoided. The observed side effects were marginal."
A research published in Pharmacol Biochem in 2004 showed that delta-8 THC, also at extremely low doses, improved appetite and cognitive function in mice. 'Delta(8)-THC (0.001 mg/kg) caused increased food intake and a propensity to enhance cognitive function without cannabimimetic side effects. Therefore a low dose of THC could be a possible therapeutic agent in the treatment of weight disorders with limited side effects associated with cannabis use."
A review by Cannabinoid and Cannabis Research in 2018 demonstrated potential for the treatment of pain and inflammation with topical delta-8 THC and CBD) "Our results provide novel evidence that phytocannabinoids Δ8THC and CBD... are antinociceptive and anti-inflammatory in an experimental corneal hyperalgesia model."
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